2008 Annual Report - Contents
Board of Scientific Counselors
Workshops and Conferences Organized by NICHD Intramural Research Program Staff in 2008
- Cell Biology and Metabolism Program: Juan Bonifacino, Program Director
- Irwin Arias: Molecular and Cellular Mechanisms of Hepatocellular Polarity and Biliary Secretion in Health and Cholestasis
- Juan Bonifacino: Protein Sorting in the Endosomal-Lysosomal System
- Ramanujan Hegde: Regulation of Secretory and Membrane Protein Biogenesis
- Mary Lilly: Cell Cycle Regulation in Oogenesis
- Jennifer Lippincott-Schwartz: Dynamics of Membrane Trafficking, Sorting, and Compartmentalization within Eukaryotic Cells
- Gisela Storz: Small Noncoding RNAs and Small ORFs
- Program in Cellular Regulation and Metabolism: Alan Hinnebusch, Program Director
- Mary Dasso: Mitotic Regulation in Higher Eukaryotes by Ran and SUMO-1
- Thomas Dever: Mechanism and Regulation of Eukaryotic Protein Synthesis
- Alan Hinnebusch: Transcriptional and Translational Regulatory Mechanisms in Nutrient Control of Gene Expression
- Chi-Hon Lee: Development and Function of Drosophila Visual Circuits
- Henry Levin: Retrotransposons as Models for the Replication of Retroviruses
- Mihaela Serpe: Biochemical Genetics of Signal Transduction
- Yun-Bo Shi: Molecular Mechanism of Frog Metamorphosis
- Alexander Strunnikov: SMC Family Proteins and Associated Factors in Mitotic Chromosome Segregation
- Roger Woodgate: Studies on DNA Replication, Repair, and Mutagenesis in Eukaryotic and Prokaryotic Cells
- Program in Developmental and Molecular Immunity: John Robbins, Rachel Schneerson, Joint Program Directors
- John Robbins and Rachel Schneerson: Development of Vaccines Against Bacterial Diseases, Especially in Children
- Program in Developmental Endocrinology and Genetics: Constantine Stratakis, Program Director
- Greti Aguilera: Neuroendocrinology of Stress
- Jeffrey Baron: Regulation of Childhood Growth
- Carolyn Bondy: The X-Chromosome and Gender Effects in Physiology, Pathophysiology, and Longevity
- Kevin Catt: Peptide Hormone Receptors and Signal Transduction
- Janice Chou: Molecular Genetics of Heritable Human Disorders
- Maria Dufau: Receptors and Actions of Peptide Hormones and Regulatory Proteins in Endocrine Mechanisms
- David Klein: Pineal Gland and Chronobiology
- Anil Mukherjee: Heritable Neurodegenerative and Autoimmune Disorders
- Ida Owens: Molecular Biology, Regulation, and Biochemistry of UDP-Glucuronosyltransferase Isozymes
- Forbes Porter: Cholesterol Deficiency and Genetic Syndromes
- Constantine Stratakis: Molecular Genetics of Adrenocortical Tumors and Related Disorders
- Charles Strott: The Biotransformation of Endobiotics by Sulfonation
- Jack Yanovski: Physiology, Psychology, and Genetics of Obesity
- Program in Developmental Neuroscience: Chris McBain, Program Director
- Tamás Balla: Phosphatidylinositol 4-Kinases and Cell Regulation
- Marc Bornstein: Child and Family Development Across the First Two Decades of Life
- Andres Buonanno: Developmental Regulation of Neuronal and Muscle Plasticity
- Dax Hoffman: Potassium Channels and Dendritic Function in Hippocampal Pyramidal Neurons
- Kuo-Ping Huang: Signal Transduction in Synaptic Transmission and Plasticity
- Y. Peng Loh: Secretory Protein Trafficking and Granule Biogenesis in Neuroendocrine Cells and Role of Carboxypeptidase E Splice Isoform in Tumor Growth and Metastasis
- Bai Lu: Neurotrophic Regulation of Synapse Development and Plasticity
- Mark Mayer: Glutamate Receptor Structural Biology
- Chris McBain: Hippocampal Interneurons and Their Role in the Control of Network Excitability
- John Newman: Neuroethology of Crying
- James Russell: Calcium-Based Excitability in Glial Cells
- Stanko Stojilkovic: Signaling and Secretion in Neuroendocrine Cells
- Mark Stopfer: Olfactory Coding and Decoding by Ensembles of Neurons
- Stephen Suomi: Genetic and Environmental Determinants of Primate Biobehavioral Development
- Program in Genomics of Differentiation: Igor Dawid, Program Director
- Sohyun Ahn: Molecular Genetics of Neural Stem Cells
- Michael Cashel: Integration of Bacterial Nutritional Responses
- Ajay Chitnis: Dynamic Regulation of Notch Signaling During Zebrafish Neurogenesis
- David Clark: Chromatin Remodeling and Gene Activation
- Robert Crouch: Physiological, Biochemical, and Molecular-Genetic Events of Recognition and Resolution of RNA/DNA Hybrids
- Igor Dawid: Molecular Genetics of Embryogenesis in Xenopus and Zebrafish
- Melvin DePamphilis: Regulation of Mammalian Cell Proliferation and Development
- Bruce Howard: The Chromatin-Based Epigenome in Development and Aging
- Judith Kassis: Control of Gene Expression During Development
- James Kennison: Regulation of Homeotic Gene Function in Drosophila
- Judith Levin: Molecular Genetics of Mammalian Retrovirus Replication
- Paul Love: Genes and Signals Regulating Mammalian Hematopoiesis
- Richard Maraia: La Antigen, RNA Polymerase III, and Associated RNA Metabolism in Cell Biology, Growth, and Development
- Keiko Ozato: Developmental Gene Regulation of the Immune System
- Karl Pfeifer: Molecular Genetics of an Imprinted Gene Cluster on Mouse Distal Chromosome 7
- Thomas Sargent: Control of Ectodermal Development in Vertebrate Embryos
- Brant Weinstein: Organogenesis of the Zebrafish Vasculature
- Robert Weisberg: Mechanisms for Controlling Gene Expression in Bacteria and Bacteriophage
- Heiner Westphal: Genes that Control Mouse Development
- Program in Molecular Medicine: Tracey Rouault, Program Director
- Stephen Kaler: Translational Research on Inherited Pediatric Diseases
- Tracey Rouault: Regulation of Intracellular Iron Metabolism
- Program in Perinatal Research and Obstetrics: Roberto Romero, Program Director
- Program in Physical Biology: Joshua Zimmerberg, Program Director
- Peter Basser: Tissue Biophysics and Biomimetics
- Sergey Bezrukov: Biophysics of Large Membrane Channels
- Robert Bonner: Medical Biophysics
- Leonid Chernomordik: Membrane Fusion Mediated by Viral and Developmental Protein Fusogens
- Amir Gandjbakhche: Quantitative Biophotonics for Tissue Characterization and Function
- Leonid Margolis: HIV Pathogens in Human Lymphoid Tissue
- Ralph Nossal: Cell Biophysics
- Adrian Parsegian: Physical Forces Organizing Biomolecules
- Donald Rau: Intermolecular Forces, Recognition, and Dynamics
- Joshua Zimmerberg: Membrane Remodeling During Viral Infection, Parasite Invasion, and Apoptosis; Components and Kinetics in Exocytosis
- Program in Reproductive and Adult Endocrinology: Alan DeCherney, Program Director
- Wai-Yee Chan: Regulation of Gene Expression, Cellular Proliferation, and Differentiation in Mammalian Development
- Alan DeCherney: Reproductive Endocrinology and Science
- Tomoshige Kino: Target Tissue Glucocorticoid Signaling: Basic and Clinical Implications
- Lawrence Nelson: The Menstrual Cycle and Human Reproduction
- Lynnette Nieman: Investigation of Adrenal Gland Disorders and Disorders of Female Reproduction
- Karel Pacak: Diagnosis, Localization, Pathophysiology, and Molecular Biology of Pheochromocytoma
- Owen Rennert: Genetic and Genomic Studies in Normal Development and Diseases
- James Segars: Reproductive Endocrinology and Infertility
- Bone and Extracellular Matrix Branch
- Joan Marini: Genetic Disorders of Bone and Extracellular Matrix
- Section on Nervous System Development and Plasticity
- Douglas Fields: Nervous System Development and Plasticity
- Section on Physical Biochemistry
- Scientific Core Facilities
- Jonathan Epstein: Scientific Software Support and Bioinformatics
- James Russell: Microscopy and Imaging
- Alfred Yergey and Peter Backlund: Mass Spectrometry